Thursday, October 16, 2025

Why we want a brand new measure of maternal well being: the “lifetime threat of maternal close to miss” – IJEblog


Ursula Gazeley

In accordance with the latest knowledge from the World Well being Group, the lifetime threat of maternal demise for a lady in Chad is a staggering 1 in 15, in contrast with 1 in 43,000 in Norway. Because of this a woman in Chad has an nearly 3000 instances larger threat of dying from a maternal trigger throughout her reproductive lifetime than a woman in Norway. The lifetime threat of maternal demise is a helpful measure to assist us perceive this world inequality in maternal mortality.

Maternal demise is a tragic final result of being pregnant. Though it’s now uncommon in most elements of the world, progress is slowing. Moreover, many extra ladies expertise extreme being pregnant problems that carry them dangerously near demise — so shut that they’re very more likely to want emergency hospital care to save lots of their lives. Such occasions are referred to as “maternal close to misses” and are recognized primarily based on organ dysfunction (e.g. cardiovascular, respiratory, renal, haematological, hepatic or neurological) or complication-specific standards, comparable to eclampsia, septicaemia or the necessity for hysterectomy or blood transfusion following obstetric haemorrhage.

Maternal close to miss is a vital maternal well being final result that displays a well being care system’s means to offer emergency obstetric care and save a girl’s life when problems come up. Furthermore, experiencing such extreme problems can have long-term penalties for a lady’s bodily, psychological, sexual, social and financial wellbeing.

There have been many calls to enhance metrics on maternal morbidity, however comparatively little progress in reaching this. In our current examine, revealed within the IJE, we introduce a brand new measure referred to as the “lifetime threat of maternal close to miss” to estimate the burden of maternal close to miss morbidity throughout ladies’s reproductive lifetimes. This measure is analogous to the lifetime threat of maternal demise, utilized to life-threatening morbidity.

Present indicators of maternal close to miss prevalence — each the maternal close to miss ratio and maternal close to miss charge — solely account for the extent of obstetric threat related to a given being pregnant. Neither measure accounts for the dangers related to fertility ranges (ladies are prone to experiencing a close to miss throughout every being pregnant they’ve), nor ladies’s possibilities of surviving the reproductive ages of 15–49 years (to expertise a close to miss, a girl should not have died from a maternal trigger or the rest). The lifetime threat of maternal close to miss addresses these deficits and captures the dynamics related to obstetric threat, fertility ranges and ladies’s reproductive age survival.

In our examine, we demonstrated use of this measure in Namibia. Our estimates point out {that a} 15-year-old lady in Namibia faces a 1 in 38 lifetime threat of experiencing a maternal close to miss, in contrast with a 1 in 142 lifetime threat of maternal demise. When these dangers are mixed, the lady has a 1 in 30 probability of both dying from a maternal trigger or experiencing a near-miss complication throughout her reproductive years.

This mixed lifetime threat of maternal demise or close to miss is a vital instrument for advocacy — to focus on the influence of maternal well being on ladies’s lives and the necessity for the worldwide group to redouble its efforts to finish preventable maternal mortality and morbidity. Estimation is required throughout high- and low-income settings to attract consideration to world inequities in antagonistic being pregnant outcomes.

To measure a rustic’s lifetime threat of maternal close to miss, the perfect state of affairs is to make use of nationally consultant knowledge on the maternal close to miss ratio (the variety of maternal close to misses per 1000 reside births). The variety of maternal close to misses can solely come from well being care services. In international locations the place many ladies give beginning at dwelling, the variety of reside births ought to come from population-based estimates, in order that births at dwelling are additionally counted.

Throughout all world areas, births in well being care services are lowest in sub-Saharan Africa. We’ll subsequently overestimate the lifetime threat of maternal close to miss if we depend on (unadjusted) facility-based estimates of births in these settings. In our examine, we selected to use this indicator to Namibia as a result of, though it’s a high-burden setting, high-quality nationwide population-based maternal close to miss surveillance knowledge have been obtainable.

To start out measuring the lifetime threat of maternal close to miss globally, extra international locations have to routinely measure and report what number of maternal close to misses happen on the nationwide degree, as they do for maternal deaths. A number of high-income international locations already report this repeatedly (e.g. the Scottish Confidential Audit of Extreme Maternal Morbidity and the Irish Nationwide Audit of Extreme Maternal Morbidity). Except for the maternal close to miss ratio, all different knowledge required to estimate the lifetime threat of maternal close to miss can be found by way of open entry from World Inhabitants Prospects.

Learn extra:

Gazeley U, Polizzi A, Romero-Prieto JE, et al. Lifetime threat of maternal close to miss morbidity: a novel indicator of maternal well being. Int J Epidemiol 2023; 18 December. doi: 10.1093/ije/dyad169


Ursula Gazeley (@GazeleyUrsula) is a PhD scholar on the London Faculty of Hygiene and Tropical Medication. Her analysis pursuits give attention to measurement challenges of maternal mortality and morbidity, together with outcomes past the 42-day postpartum interval.



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